Dear Colleagues,
As part of the establishment of a National Multidisciplinary Advisory Board (MAB) for Cancer Predisposition in Children, Adolescents and Young Adults (C-AYA), we are reaching out to identify professionals in Belgium involved in the care and/or research of cancer predispositions and predisposition genes.
The MAB will serve as a national platform for multidisciplinary discussions of complex or uncertain cases and provide expert advice on:
- Diagnostic work-up: clinical criteria, genetic testing options, suspected predispositions without confirmed diagnosis, …
- Management: treatment, follow-up (risk reduction, early detection, interception), atypical presentations of known predispositions, …
- Interpretation and additional work-up of (putative) germline results: variants of unknown significance (VUS), incidental or secondary findings, mutations in predisposition genes identified in malignant samples with potential germline origin, …
- Referral to European experts (e.g., ERN Genturis).
Through case discussions, the MAB will offer opportunities to share knowledge and experience and exchange of best practices.
To support this initiative, we kindly ask you to complete a brief survey (around 5 minutes) designed to map expertise and identify potential contributors to this effort.
Survey link: https://surveys.sciensano.be/index.php/476172?lang=en
Deadline: October 13, 2025
Your participation will be greatly valued and will contribute meaningfully to strengthening hereditary cancer care and research in Belgium.
We would also be very grateful if you could share this invitation with colleagues or networks who may be interested or relevant to this initiative.
Thank you for your time and consideration.
Should you have any questions or comments, please do not hesitate to contact: mariavaleria.freirechadrina@sciensano.be
